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Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region

The coiled-coil motif mediates subunit oligomerization and scaffolding and underlies several fundamental biologic processes. Prohibitins (PHBs), mitochondrial inner membrane proteins involved in mitochondrial homeostasis and signal transduction, are predicted to have a coiled-coil motif, but their s...

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Detalles Bibliográficos
Autores principales: Yoshinaka, Takahiro, Kosako, Hidetaka, Yoshizumi, Takuma, Furukawa, Ryo, Hirano, Yu, Kuge, Osamu, Tamada, Taro, Koshiba, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745515/
https://www.ncbi.nlm.nih.gov/pubmed/31522117
http://dx.doi.org/10.1016/j.isci.2019.08.056