Expression of the Mxra8 Receptor Promotes Alphavirus Infection and Pathogenesis in Mice and Drosophila

Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O’nyong nyong (ONNV) viruses. To determine its role in pathogenesis, we generated mice with mutant Mxra8 alleles: an 8-nucleotide deletion that produces a truncated,...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Earnest, James T., Kim, Arthur S., Winkler, Emma S., Desai, Pritesh, Adams, Lucas J., Hu, Gaowei, Bullock, Christopher, Gold, Beth, Cherry, Sara, Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745702/
https://www.ncbi.nlm.nih.gov/pubmed/31484075
http://dx.doi.org/10.1016/j.celrep.2019.07.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745702/
https://www.ncbi.nlm.nih.gov/pubmed/31484075
http://dx.doi.org/10.1016/j.celrep.2019.07.105

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