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Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity

OBJECTIVE: To investigate the use of muscle MRI for the differential diagnosis and as a disease progression biomarker for 2 major forms of motor neuron disorders: spinal bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS). METHODS: We applied quantitative 3-point Dixon and semiqua...

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Detalles Bibliográficos
Autores principales: Klickovic, Uros, Zampedri, Luca, Sinclair, Christopher D.J., Wastling, Stephen J., Trimmel, Karin, Howard, Robin S., Malaspina, Andrea, Sharma, Nikhil, Sidle, Katie, Emira, Ahmed, Shah, Sachit, Yousry, Tarek A., Hanna, Michael G., Greensmith, Linda, Morrow, Jasper M., Thornton, John S., Fratta, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745729/
https://www.ncbi.nlm.nih.gov/pubmed/31391248
http://dx.doi.org/10.1212/WNL.0000000000008009