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Skeletal muscle MRI differentiates SBMA and ALS and correlates with disease severity
OBJECTIVE: To investigate the use of muscle MRI for the differential diagnosis and as a disease progression biomarker for 2 major forms of motor neuron disorders: spinal bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS). METHODS: We applied quantitative 3-point Dixon and semiqua...
Autores principales: | Klickovic, Uros, Zampedri, Luca, Sinclair, Christopher D.J., Wastling, Stephen J., Trimmel, Karin, Howard, Robin S., Malaspina, Andrea, Sharma, Nikhil, Sidle, Katie, Emira, Ahmed, Shah, Sachit, Yousry, Tarek A., Hanna, Michael G., Greensmith, Linda, Morrow, Jasper M., Thornton, John S., Fratta, Pietro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745729/ https://www.ncbi.nlm.nih.gov/pubmed/31391248 http://dx.doi.org/10.1212/WNL.0000000000008009 |
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