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Multiplex methylated DNA testing in plasma with high sensitivity and specificity for colorectal cancer screening

Methylated SEPT9 showed relatively low sensitivity in detecting early stage colorectal cancer (CRC) and advanced adenomas (AA) in plasma. Combination of multiple biomarkers was an effective strategy to improve sensitivity in early stage cancer diagnosis and screening. A new qPCR‐based assay combinin...

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Detalles Bibliográficos
Autores principales: Zhao, Guodong, Li, Hui, Yang, Zixuan, Wang, Zhenzhen, Xu, Manqiu, Xiong, Shangmin, Li, Shiming, Wu, XiaoTing, Liu, Xiaoyu, Wang, Ziwen, Zhu, Yun, Ma, Yong, Fei, Sujuan, Zheng, Minxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745865/
https://www.ncbi.nlm.nih.gov/pubmed/31407497
http://dx.doi.org/10.1002/cam4.2475