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Anagrelide Modulates Proplatelet Formation Resulting in Decreased Number and Increased Size of Platelets

We retrospectively evaluated 48 essential thrombocythemia (ET) patients who were treated in our institute (male/female, 14/34, median age, 61.5 years). In 14 patients treated with anagrelide (ANA), the degree of platelet count reduction (median, −56.6%) was strongly correlated with increase of mean...

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Detalles Bibliográficos
Autores principales: Miyashita, Naohiro, Onozawa, Masahiro, Yokoyama, Shota, Hidaka, Daisuke, Hayasaka, Koji, Kunishima, Shinji, Teshima, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745917/
https://www.ncbi.nlm.nih.gov/pubmed/31723843
http://dx.doi.org/10.1097/HS9.0000000000000268