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The Impact of the Cellular Origin in Acute Myeloid Leukemia: Learning From Mouse Models
Acute myeloid leukemia (AML) is a genetically heterogeneous disease driven by a limited number of cooperating mutations. There is a long-standing debate as to whether AML driver mutations occur in hematopoietic stem or in more committed progenitor cells. Here, we review how different mouse models, d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer Health
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745939/ https://www.ncbi.nlm.nih.gov/pubmed/31723801 http://dx.doi.org/10.1097/HS9.0000000000000152 |