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The Impact of PI3-kinase/RAS Pathway Cooperating Mutations in the Evolution of KMT2A-rearranged Leukemia

Leukemia is an evolutionary disease and evolves by the accrual of mutations within a clone. Those mutations that are systematically found in all the patients affected by a certain leukemia are called “drivers” as they are necessary to drive the development of leukemia. Those ones that accumulate ove...

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Detalles Bibliográficos
Autor principal: Esposito, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746018/
https://www.ncbi.nlm.nih.gov/pubmed/31723831
http://dx.doi.org/10.1097/HS9.0000000000000195