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The Impact of PI3-kinase/RAS Pathway Cooperating Mutations in the Evolution of KMT2A-rearranged Leukemia
Leukemia is an evolutionary disease and evolves by the accrual of mutations within a clone. Those mutations that are systematically found in all the patients affected by a certain leukemia are called “drivers” as they are necessary to drive the development of leukemia. Those ones that accumulate ove...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer Health
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746018/ https://www.ncbi.nlm.nih.gov/pubmed/31723831 http://dx.doi.org/10.1097/HS9.0000000000000195 |