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In the Eye of the Storm: Immune-mediated Toxicities Associated With CAR-T Cell Therapy

The success of chimeric antigen receptor (CAR)-T cell therapy with impressive response rates in hematologic malignancies but also promising data in solid tumors came along with the cognition of unexpected, potentially life-threatening immune-mediated toxicities, namely the cytokine release syndrome...

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Detalles Bibliográficos
Autores principales: Garcia Borrega, Jorge, Gödel, Philipp, Rüger, Maria Adele, Onur, Özgür A., Shimabukuro-Vornhagen, Alexander, Kochanek, Matthias, Böll, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746039/
https://www.ncbi.nlm.nih.gov/pubmed/31723828
http://dx.doi.org/10.1097/HS9.0000000000000191