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Human Platelet Lysate Media Supplement Supports Lentiviral Transduction and Expansion of Human T Lymphocytes While Maintaining Memory Phenotype

Immune cell therapy has emerged as a promising approach to treat malignancies that were up until recently only treated on a palliative basis. Chimeric antigen receptor- (CAR-) modified T lymphocytes (T cells) in particular have proven to be very effective for certain hematological malignancies. The...

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Detalles Bibliográficos
Autores principales: Canestrari, Emanuele, Steidinger, Hayley R., McSwain, Brianna, Charlebois, Steven J., Dann, Christina Tenenhaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746159/
https://www.ncbi.nlm.nih.gov/pubmed/31565660
http://dx.doi.org/10.1155/2019/3616120