Cargando…

Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication

Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein response (UPR). The most conserved pathway to trig...

Descripción completa

Detalles Bibliográficos
Autores principales: Rohde, Cornelius, Becker, Stephan, Krähling, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746283/
https://www.ncbi.nlm.nih.gov/pubmed/31495285
http://dx.doi.org/10.1080/22221751.2019.1659552