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Marburg virus regulates the IRE1/XBP1-dependent unfolded protein response to ensure efficient viral replication
Viruses regulate cellular signalling pathways to ensure optimal viral replication. During Marburg virus (MARV) infection, large quantities of the viral glycoprotein GP are produced in the ER; this may result in the activation of the unfolded protein response (UPR). The most conserved pathway to trig...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746283/ https://www.ncbi.nlm.nih.gov/pubmed/31495285 http://dx.doi.org/10.1080/22221751.2019.1659552 |