Mutations in the H7 HA and PB1 genes of avian influenza a viruses increase viral pathogenicity and contact transmission in guinea pigs

Avian influenza A viruses (AIV) of the H7 subtype continue to evolve posing a pandemic threat. However, molecular markers of H7N7 AIV pathogenicity and transmission in mammals remain poorly understood. In this study, we performed a systematic in vitro and in vivo analysis by comparing an H7N7 highly...

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Detalles Bibliográficos
Autores principales: Dreier, Carola, Resa-Infante, Patricia, Thiele, Swantje, Stanelle-Bertram, Stephanie, Walendy-Gnirß, Kerstin, Speiseder, Thomas, Preuss, Annette, Müller, Zacharias, Klenk, Hans-Dieter, Stech, Jürgen, Gabriel, Gülsah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746284/
https://www.ncbi.nlm.nih.gov/pubmed/31503518
http://dx.doi.org/10.1080/22221751.2019.1663131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746284/
https://www.ncbi.nlm.nih.gov/pubmed/31503518
http://dx.doi.org/10.1080/22221751.2019.1663131

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