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GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve

GPR40/FFAR1 is a Gq protein-coupled receptor expressed in pancreatic β cells and enteroendocrine cells, and mediates insulin and incretin secretion to regulate feeding behavior. Several GPR40 full agonists have been reported to reduce food intake in rodents by regulating gut hormone secretion in add...

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Detalles Bibliográficos
Autores principales: Ueno, Hikaru, Ito, Ryo, Abe, Shin-ichi, Ogino, Hitomi, Maruyama, Minoru, Miyashita, Hirohisa, Miyamoto, Yasufumi, Moritoh, Yusuke, Tsujihata, Yoshiyuki, Takeuchi, Koji, Nishigaki, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746387/
https://www.ncbi.nlm.nih.gov/pubmed/31525244
http://dx.doi.org/10.1371/journal.pone.0222653