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GPR40 full agonism exerts feeding suppression and weight loss through afferent vagal nerve
GPR40/FFAR1 is a Gq protein-coupled receptor expressed in pancreatic β cells and enteroendocrine cells, and mediates insulin and incretin secretion to regulate feeding behavior. Several GPR40 full agonists have been reported to reduce food intake in rodents by regulating gut hormone secretion in add...
Autores principales: | Ueno, Hikaru, Ito, Ryo, Abe, Shin-ichi, Ogino, Hitomi, Maruyama, Minoru, Miyashita, Hirohisa, Miyamoto, Yasufumi, Moritoh, Yusuke, Tsujihata, Yoshiyuki, Takeuchi, Koji, Nishigaki, Nobuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746387/ https://www.ncbi.nlm.nih.gov/pubmed/31525244 http://dx.doi.org/10.1371/journal.pone.0222653 |
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