TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala

TMEM16B (ANO2) is the Ca(2+)-activated chloride channel expressed in multiple brain regions, including the amygdala. Here we report that Ano2 knockout mice exhibit impaired anxiety-related behaviors and context-independent fear memory, thus implicating TMEM16B in anxiety modulation. We found that TM...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ke-Xin, He, Mu, Ye, Wenlei, Simms, Jeffrey, Gill, Michael, Xiang, Xuaner, Jan, Yuh Nung, Jan, Lily Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746550/
https://www.ncbi.nlm.nih.gov/pubmed/31482844
http://dx.doi.org/10.7554/eLife.47106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746550/
https://www.ncbi.nlm.nih.gov/pubmed/31482844
http://dx.doi.org/10.7554/eLife.47106

Ejemplares similares