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In Vitro Study of the Enzymatic and Nonenzymatic Conjugation of Treosulfan with Glutathione
BACKGROUND AND OBJECTIVES: Treosulfan (dihydroxybusulfan), licensed for the treatment of ovarian carcinoma, is investigated in clinical trials as a myeloablative agent for conditioning prior to hematopoietic stem cell transplantation. Clinical experience shows that treosulfan exhibits lower organ to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746681/ https://www.ncbi.nlm.nih.gov/pubmed/30993552 http://dx.doi.org/10.1007/s13318-019-00555-x |