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Pharmacokinetics and Safety of a Diclofenac Sodium 75 mg/1 mL Solution (Akis(®)/Dicloin(®)) Administered as a Single Intravenous Bolus Injection in Healthy Men and Women

BACKGROUND: A 1-mL aqueous solution for parenteral injection containing diclofenac sodium and hydroxypropyl-β-cyclodextrin, presently on the market for intramuscular and subcutaneous administration (Akis(®)/Dicloin(®)), was further developed for intravenous (i.v.) bolus administration. OBJECTIVES: T...

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Detalles Bibliográficos
Autores principales: Leuratti, Chiara, Loprete, Luca, Rossini, Matteo, Frangione, Valeria, Rovati, Stefano, Radicioni, Milko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746683/
https://www.ncbi.nlm.nih.gov/pubmed/31077065
http://dx.doi.org/10.1007/s13318-019-00558-8