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Clinical and Pharmacokinetic Outcomes of Peak–Trough-Based Versus Trough-Based Vancomycin Therapeutic Drug Monitoring Approaches: A Pragmatic Randomized Controlled Trial

BACKGROUND: Vancomycin therapeutic drug monitoring (TDM) is based on achieving 24-h area under the concentration–time curve to minimum inhibitory concentration cure breakpoints (AUC(24)/MIC). Approaches to vancomycin TDM vary, with no head-to-head randomized controlled trial (RCT) comparisons to dat...

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Detalles Bibliográficos
Autores principales: Al-Sulaiti, Fatima Khalifa, Nader, Ahmed Mohamed, Saad, Mohamed Omar, Shaukat, Adila, Parakadavathu, Rakesh, Elzubair, Ahmed, Al-Badriyeh, Daoud, Elewa, Hazem, Awaisu, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746691/
https://www.ncbi.nlm.nih.gov/pubmed/30919233
http://dx.doi.org/10.1007/s13318-019-00551-1