A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas

Pancreatic ductal adenocarcinomas (PDAC) are deadly on account of the delay in diagnosis and dearth of effective treatment options for advanced disease. The insurmountable hurdle of targeting oncogene KRAS, the most prevalent genetic mutation in PDAC, has delayed the availability of targeted therapy...

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Detalles Bibliográficos
Autores principales: Parameswaran, Neetha, Bartel, Courtney A., Hernandez-Sanchez, Wilnelly, Miskimen, Kristy L., Smigiel, Jacob M., Khalil, Ahmad M., Jackson, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746704/
https://www.ncbi.nlm.nih.gov/pubmed/31527715
http://dx.doi.org/10.1038/s41598-019-49475-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746704/
https://www.ncbi.nlm.nih.gov/pubmed/31527715
http://dx.doi.org/10.1038/s41598-019-49475-5

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