Early Life Supraphysiological Levels of Oxygen Exposure Permanently Impairs Hippocampal Mitochondrial Function

Preterm infants requiring prolonged oxygen therapy often develop cognitive dysfunction in later life. Previously, we reported that 14-week-old young adult mice exposed to hyperoxia as newborns had spatial and learning deficits and hippocampal shrinkage. We hypothesized that the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Ramani, Manimaran, Miller, Kiara, Brown, Jamelle, Kumar, Ranjit, Kadasamy, Jegen, McMahon, Lori, Ballinger, Scott, Ambalavanan, Namasivayam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746707/
https://www.ncbi.nlm.nih.gov/pubmed/31527593
http://dx.doi.org/10.1038/s41598-019-49532-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746707/
https://www.ncbi.nlm.nih.gov/pubmed/31527593
http://dx.doi.org/10.1038/s41598-019-49532-z

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