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Early Life Supraphysiological Levels of Oxygen Exposure Permanently Impairs Hippocampal Mitochondrial Function
Preterm infants requiring prolonged oxygen therapy often develop cognitive dysfunction in later life. Previously, we reported that 14-week-old young adult mice exposed to hyperoxia as newborns had spatial and learning deficits and hippocampal shrinkage. We hypothesized that the underlying mechanism...
Autores principales: | Ramani, Manimaran, Miller, Kiara, Brown, Jamelle, Kumar, Ranjit, Kadasamy, Jegen, McMahon, Lori, Ballinger, Scott, Ambalavanan, Namasivayam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746707/ https://www.ncbi.nlm.nih.gov/pubmed/31527593 http://dx.doi.org/10.1038/s41598-019-49532-z |
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