An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis

Conventional chemotherapy is mostly effective in the treatment of rapidly-dividing differentiated tumor cells but has limited application toward eliminating cancer stem cell (CSC) population. The presence of a very small number of CSCs may contribute to the development of therapeutic resistance, met...

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Detalles Bibliográficos
Autores principales: Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Trávníček, Zdeněk, Brabec, Viktor, Kasparkova, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746710/
https://www.ncbi.nlm.nih.gov/pubmed/31527683
http://dx.doi.org/10.1038/s41598-019-49774-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746710/
https://www.ncbi.nlm.nih.gov/pubmed/31527683
http://dx.doi.org/10.1038/s41598-019-49774-x

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