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An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis
Conventional chemotherapy is mostly effective in the treatment of rapidly-dividing differentiated tumor cells but has limited application toward eliminating cancer stem cell (CSC) population. The presence of a very small number of CSCs may contribute to the development of therapeutic resistance, met...
Autores principales: | Novohradsky, Vojtech, Markova, Lenka, Kostrhunova, Hana, Trávníček, Zdeněk, Brabec, Viktor, Kasparkova, Jana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746710/ https://www.ncbi.nlm.nih.gov/pubmed/31527683 http://dx.doi.org/10.1038/s41598-019-49774-x |
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