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A novel conditional ZsGreen-expressing transgenic reporter rat strain for validating Cre recombinase expression
The Cre/loxP recombination system has revolutionized the ability to genetically manipulate animal genomes in order to conditionally control gene expression. With recent advances in genome editing, barriers to manipulating the rat genome have been overcome and it is now possible to generate new rat s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746712/ https://www.ncbi.nlm.nih.gov/pubmed/31527612 http://dx.doi.org/10.1038/s41598-019-49783-w |