CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis

A major challenge in regenerative medicine is the repair of injured neurons. Regeneration of laser-cut C. elegans neurons requires early action of core apoptosis activator CED-4/Apaf1 and CED-3/caspase. While testing models for CED-4 as a candidate calcium-sensitive activator of repair, we unexpecte...

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Detalles Bibliográficos
Autores principales: Wang, Guoqiang, Sun, Lin, Reina, Christopher P., Song, Isaac, Gabel, Christopher V., Driscoll, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746752/
https://www.ncbi.nlm.nih.gov/pubmed/31527664
http://dx.doi.org/10.1038/s41598-019-49633-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746752/
https://www.ncbi.nlm.nih.gov/pubmed/31527664
http://dx.doi.org/10.1038/s41598-019-49633-9

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