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CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis
A major challenge in regenerative medicine is the repair of injured neurons. Regeneration of laser-cut C. elegans neurons requires early action of core apoptosis activator CED-4/Apaf1 and CED-3/caspase. While testing models for CED-4 as a candidate calcium-sensitive activator of repair, we unexpecte...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746752/ https://www.ncbi.nlm.nih.gov/pubmed/31527664 http://dx.doi.org/10.1038/s41598-019-49633-9 |