Hypoxia Activates the PTHrP –MEF2C Pathway to Attenuate Hypertrophy in Mesenchymal Stem Cell Derived Cartilage

Articular cartilage lacks an intrinsic repair capacity and due to the ability of mesenchymal stem cells (MSCs) to differentiate into chondrocytes, MSCs have been touted as a cellular source to regenerate damaged cartilage. However, a number of prevailing concerns for such a treatment remain. General...

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Detalles Bibliográficos
Autores principales: Browe, David C., Coleman, Cynthia M., Barry, Frank P., Elliman, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746812/
https://www.ncbi.nlm.nih.gov/pubmed/31527619
http://dx.doi.org/10.1038/s41598-019-49499-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746812/
https://www.ncbi.nlm.nih.gov/pubmed/31527619
http://dx.doi.org/10.1038/s41598-019-49499-x

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