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Anti-tumor activity of BET inhibitors in androgen-receptor-expressing triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a heterogeneous disease comprising several subtypes. Androgen-receptor (AR) signaling has been targeted by several investigational agents in luminal AR subtype TNBCs. Bromodomain (BRD) and extra-terminal motif (BET) protein inhibitors have been shown to attenu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746817/ https://www.ncbi.nlm.nih.gov/pubmed/31527644 http://dx.doi.org/10.1038/s41598-019-49366-9 |