Loss of Janus Associated Kinase 1 Alters Urothelial Cell Function and Facilitates the Development of Bladder Cancer

Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune responses or a direct role for PID germline mutations in tumorigenesis. We recently identified germline loss of function mutations in Janus Associated Kina...

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Detalles Bibliográficos
Autores principales: Daza-Cajigal, Vanessa, Albuquerque, Adriana S., Pearson, Joanna, Hinley, Jennifer, Mason, Andrew S., Stahlschmidt, Jens, Thrasher, Adrian J., Mishra, Vibhash, Southgate, Jennifer, Burns, Siobhan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746825/
https://www.ncbi.nlm.nih.gov/pubmed/31552026
http://dx.doi.org/10.3389/fimmu.2019.02065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746825/
https://www.ncbi.nlm.nih.gov/pubmed/31552026
http://dx.doi.org/10.3389/fimmu.2019.02065

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