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Platelet P-selectin triggers rapid surface exposure of tissue factor in monocytes

Tissue factor (TF) plays a central role in haemostasis and thrombosis. Following vascular damage, vessel wall TF initiates the extrinsic coagulation cascade. TF can also be exposed by monocytes. Inflammatory or infectious stimuli trigger synthesis of new TF protein by monocytes over the course of ho...

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Detalles Bibliográficos
Autores principales: Ivanov, Ivelin I., Apta, Bonita H. R., Bonna, Arkadiusz M., Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746844/
https://www.ncbi.nlm.nih.gov/pubmed/31527604
http://dx.doi.org/10.1038/s41598-019-49635-7