Cargando…

Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway

Elevated fatty acid synthase (FASN) has been reported in both androgen-dependent and -independent prostate cancers. Conventional treatment for prostate cancer is radiotherapy (RT); however, the following radiation-induced radioresistance often causes treatment failure. Upstream proteins of FASN such...

Descripción completa

Detalles Bibliográficos
Autores principales: Chuang, Hui-Yen, Lee, Yen-Po, Lin, Wei-Chan, Lin, Yi-Hsien, Hwang, Jeng-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746859/
https://www.ncbi.nlm.nih.gov/pubmed/31527721
http://dx.doi.org/10.1038/s41598-019-49486-2