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Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway
Elevated fatty acid synthase (FASN) has been reported in both androgen-dependent and -independent prostate cancers. Conventional treatment for prostate cancer is radiotherapy (RT); however, the following radiation-induced radioresistance often causes treatment failure. Upstream proteins of FASN such...
Autores principales: | Chuang, Hui-Yen, Lee, Yen-Po, Lin, Wei-Chan, Lin, Yi-Hsien, Hwang, Jeng-Jong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746859/ https://www.ncbi.nlm.nih.gov/pubmed/31527721 http://dx.doi.org/10.1038/s41598-019-49486-2 |
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