Chicken or Egg: Is Clonal Hematopoiesis Primarily Caused by Genetic or Epigenetic Aberrations?

Hematopoietic malignancies, including multiple myeloma, are associated with characteristic mutations and genetic instabilities that drive malignant transformation. On the other hand, tumor formation is also associated with drastic epigenetic aberrations, which can impact the genetic sequence. Theref...

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Detalles Bibliográficos
Autores principales: Cypris, Olivia, Božić, Tanja, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746886/
https://www.ncbi.nlm.nih.gov/pubmed/31552094
http://dx.doi.org/10.3389/fgene.2019.00785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746886/
https://www.ncbi.nlm.nih.gov/pubmed/31552094
http://dx.doi.org/10.3389/fgene.2019.00785

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