Restoration of Olfactory Memory in Drosophila Overexpressing Human Alzheimer’s Disease Associated Tau by Manipulation of L-Type Ca(2+) Channels

The cellular underpinnings of memory deficits in Alzheimer’s disease (AD) are poorly understood. We utilized the tractable neural circuits sub-serving memory in Drosophila to investigate the role of impaired Ca(2+) handling in memory deficits caused by expression of human 0N4R isoform of tau which i...

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Detalles Bibliográficos
Autores principales: Higham, James P., Hidalgo, Sergio, Buhl, Edgar, Hodge, James J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746915/
https://www.ncbi.nlm.nih.gov/pubmed/31551716
http://dx.doi.org/10.3389/fncel.2019.00409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746915/
https://www.ncbi.nlm.nih.gov/pubmed/31551716
http://dx.doi.org/10.3389/fncel.2019.00409

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