MC4R Is Involved in Neuropathic Pain by Regulating JNK Signaling Pathway After Chronic Constriction Injury

BACKGROUND: Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured neurons and glia cells. Melanocortin 4 receptor (MC4R) is involved in the regulation of pain due to its high expressions in brain. Moreover, MC4R could mediate the c-Jun N-terminal kinase (JNK) sig...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Xin, Yan, Chu, Haichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746920/
https://www.ncbi.nlm.nih.gov/pubmed/31551683
http://dx.doi.org/10.3389/fnins.2019.00919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746920/
https://www.ncbi.nlm.nih.gov/pubmed/31551683
http://dx.doi.org/10.3389/fnins.2019.00919

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