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Model-Based Evaluation of Closed-Loop Deep Brain Stimulation Controller to Adapt to Dynamic Changes in Reference Signal

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in suppressing the motor symptoms of Parkinson's disease (PD). Current clinically-deployed DBS technology operates in an open-loop fashion, i.e., fixed parameter high-frequency stimulation is delivered con...

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Detalles Bibliográficos
Autores principales: Su, Fei, Kumaravelu, Karthik, Wang, Jiang, Grill, Warren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746932/
https://www.ncbi.nlm.nih.gov/pubmed/31551704
http://dx.doi.org/10.3389/fnins.2019.00956