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Colonic Motility and Jejunal Vagal Afferent Firing Rates Are Decreased in Aged Adult Male Mice and Can Be Restored by an Aminosterol

There is a general decline in gastrointestinal function in old age including decreased intestinal motility, sensory signaling, and afferent sensitivity. There is also increased prevalence of significant constipation in aged populations. We hypothesized this may be linked to reduced colonic motility...

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Detalles Bibliográficos
Autores principales: West, Christine L., Amin, Jessica Y., Farhin, Sohana, Stanisz, Andrew M., Mao, Yu-Kang, Kunze, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746984/
https://www.ncbi.nlm.nih.gov/pubmed/31551703
http://dx.doi.org/10.3389/fnins.2019.00955