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Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins

Vascular endothelial growth factor receptor-2 (VEGFR2) and its ligands (VEGFs) are crucial players in vasculogenesis and angiogenesis. General blocking of this signaling system with antibodies or small molecule inhibitors is an established strategy to treat cancer and age-related macular degeneratio...

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Detalles Bibliográficos
Autores principales: Xie, Ye, Mansouri, Maysam, Rizk, Aurélien, Berger, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746989/
https://www.ncbi.nlm.nih.gov/pubmed/31527750
http://dx.doi.org/10.1038/s41598-019-49646-4