Cargando…

Transcription Repressor Hes1 Contributes to Neuropathic Pain Development by Modifying CDK9/RNAPII-Dependent Spinal mGluR5 Transcription

Diverse transcriptional controls in the dorsal horn have been observed in pain hypersensitivity. However, the understanding of the exact causes and mechanisms of neuropathic pain development is still fragmentary. Here, the results demonstrated nerve injury decreased the expression of spinal hairy an...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Ming-Chun, Peng, Hsien-Yu, Ho, Yu-Cheng, Lai, Cheng-Yuan, Cheng, Jen-Kun, Chen, Gin-Den, Lin, Tzer-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747068/
https://www.ncbi.nlm.nih.gov/pubmed/31454988
http://dx.doi.org/10.3390/ijms20174177