Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties

Tachyplesin I, II and III are host defense peptides from horseshoe crab species with antimicrobial and anticancer activities. They have an amphipathic β-hairpin structure, are highly positively-charged and differ by only one or two amino acid residues. In this study, we compared the structure and ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Vernen, Felicitas, Harvey, Peta J., Dias, Susana A., Veiga, Ana Salomé, Huang, Yen-Hua, Craik, David J., Lawrence, Nicole, Troeira Henriques, Sónia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747087/
https://www.ncbi.nlm.nih.gov/pubmed/31455019
http://dx.doi.org/10.3390/ijms20174184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747087/
https://www.ncbi.nlm.nih.gov/pubmed/31455019
http://dx.doi.org/10.3390/ijms20174184

Ejemplares similares