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Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties
Tachyplesin I, II and III are host defense peptides from horseshoe crab species with antimicrobial and anticancer activities. They have an amphipathic β-hairpin structure, are highly positively-charged and differ by only one or two amino acid residues. In this study, we compared the structure and ac...
Autores principales: | Vernen, Felicitas, Harvey, Peta J., Dias, Susana A., Veiga, Ana Salomé, Huang, Yen-Hua, Craik, David J., Lawrence, Nicole, Troeira Henriques, Sónia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747087/ https://www.ncbi.nlm.nih.gov/pubmed/31455019 http://dx.doi.org/10.3390/ijms20174184 |
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