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Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery
G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protein activation, or β-arrestin biased signaling, invo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747122/ https://www.ncbi.nlm.nih.gov/pubmed/31470676 http://dx.doi.org/10.3390/ijms20174237 |