Recent Insights from Molecular Dynamics Simulations for G Protein-Coupled Receptor Drug Discovery

G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protein activation, or β-arrestin biased signaling, invo...

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Detalles Bibliográficos
Autores principales: Zou, Ye, Ewalt, John, Ng, Ho-Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747122/
https://www.ncbi.nlm.nih.gov/pubmed/31470676
http://dx.doi.org/10.3390/ijms20174237

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