Investigating the Role of VDR and Megalin in Semi-Selectivity of Side-Chain Modified 19-nor Analogs of Vitamin D

1,25-dihydroxyvitamin D(3) (1,25D3) is implicated in many cellular functions, including cell proliferation and differentiation, thus exerting potential antitumor effects. A major limitation for therapeutic use of 1,25D3 are potent calcemic activities. Therefore, synthetic analogs of 1,25D3 for use i...

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Detalles Bibliográficos
Autores principales: Berkowska, Klaudia, Corcoran, Aoife, Grudzień, Małgorzata, Jakuszak, Agnieszka, Chodyński, Michał, Kutner, Andrzej, Marcinkowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747128/
https://www.ncbi.nlm.nih.gov/pubmed/31455010
http://dx.doi.org/10.3390/ijms20174183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747128/
https://www.ncbi.nlm.nih.gov/pubmed/31455010
http://dx.doi.org/10.3390/ijms20174183

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