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Human IL-23R Cytokine-Binding Homology Region-Fc Fusion Protein Ameliorates Psoriasis via the Decrease of Systemic Th17 and ILC3 Cell Responses

Interleukin (IL)-23 is considered an effective therapeutic target for the treatment of psoriasis because of the crucial role of the IL-23/IL-17 axis in the pathogenesis of psoriasis, and it has recently been reported to be involved in ILC3 cell differentiation. In this study, we report that eukaryot...

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Detalles Bibliográficos
Autores principales: Gao, Yue, Bian, Zhengying, Xue, Wenyao, Li, Qianwen, Zeng, Yu, Wang, Yimeng, Tang, Lei, Tang, Tiejun, Gao, Xiangdong, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747249/
https://www.ncbi.nlm.nih.gov/pubmed/31454926
http://dx.doi.org/10.3390/ijms20174170