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Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice

Cholesterol and bile acid (BA) homeostasis plays a central role in systemic metabolism. Accumulating evidence suggests a key regulatory function of the circadian clock, our biological timer, in lipid metabolism, particularly cholesterol and bile acid flux. Previously, we showed that Nobiletin (NOB),...

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Detalles Bibliográficos
Autores principales: Nohara, Kazunari, Nemkov, Travis, D’Alessandro, Angelo, Yoo, Seung-Hee, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747250/
https://www.ncbi.nlm.nih.gov/pubmed/31480535
http://dx.doi.org/10.3390/ijms20174281