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Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles

Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surroun...

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Detalles Bibliográficos
Autores principales: Paardekooper, Laurent M., van Vroonhoven, Ellen, ter Beest, Martin, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747261/
https://www.ncbi.nlm.nih.gov/pubmed/31450682
http://dx.doi.org/10.3390/ijms20174147