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Radical Stress Is More Cytotoxic in the Nucleus than in Other Organelles
Cells are exposed to reactive oxygen species (ROS) as a by-product of mitochondrial metabolism, especially under hypoxia. ROS are also enzymatically generated at the plasma membrane during inflammation. Radicals cause cellular damage leading to cell death, as they react indiscriminately with surroun...
Autores principales: | Paardekooper, Laurent M., van Vroonhoven, Ellen, ter Beest, Martin, van den Bogaart, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747261/ https://www.ncbi.nlm.nih.gov/pubmed/31450682 http://dx.doi.org/10.3390/ijms20174147 |
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