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Hydrogen Sulfide Prevents Elastin Loss and Attenuates Calcification Induced by High Glucose in Smooth Muscle Cells through Suppression of Stat3/Cathepsin S Signaling Pathway

Vascular calcification can be enhanced by hyperglycemia. Elastin loss in tunica media promotes the osteogenic transformation of smooth muscle cells (SMCs) and involves arterial medial calcification (AMC) that is associated with a high incidence of cardiovascular risk in patients with type 2 diabetes...

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Detalles Bibliográficos
Autores principales: Zhou, Ye-Bo, Zhou, Hong, Li, Li, Kang, Ying, Cao, Xu, Wu, Zhi-Yuan, Ding, Lei, Sethi, Gautam, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747320/
https://www.ncbi.nlm.nih.gov/pubmed/31461977
http://dx.doi.org/10.3390/ijms20174202