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New Insights into Mechanisms of Cisplatin Resistance: From Tumor Cell to Microenvironment
Although cisplatin has been a pivotal chemotherapy drug in treating patients with various types of cancer for decades, drug resistance has been a major clinical impediment. In general, cisplatin exerts cytotoxic effects in tumor cells mainly through the generation of DNA-platinum adducts and subsequ...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747329/ https://www.ncbi.nlm.nih.gov/pubmed/31450627 http://dx.doi.org/10.3390/ijms20174136 |